Cost Calculator Neditol External 2020-01-29T11:04:03+00:00

Enter the number of patients you wish to switch, to see the savings available from Neditol XL (tolterodine prolonged release capsules). Or alternatively, enter your Rx spend on generic tolterodine XL capsules, to see the savings available when you brand by Neditol XL (tolterodine XL prolonged released capsules).

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Savings based on patient numbers

Enter the number of patients to switch Tolterodine XL capsules Drug Tariff Price capsules (28)1 Neditol XL capsules (28) Cost Saving for switch to Neditol XL1* % Saving for switch to Neditol XL
4mg 50%
N/A 2mg N/A N/A N/A
      Total Month Saving
Total Patients       Total Year Saving

Or savings based on prescribing spend

Enter a generic XL capsule prescribing spend Tolterodine XL capsules Cost Saving for switch to Biquelle XL1* % Saving for switch to Biquelle XL1*
4mg 50%
N/A 2mg N/A N/A
  Total Cost Saving

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Total Savings for the patients you entered (month)
Total Savings for the patients you entered (year)
Total Prescribing Cost Savings based on your entered costs

*Based on 50% saving on the cost of Category C tolterodine prolonged-release tablets in the UK Drug Tariff.
Reference
1. January 2020 UK Drug Tariff.

Further information at www.neditol.co.uk

NEDITOL XL (Tolterodine) Prolonged-release Capsules Prescribing Information (please refer to the full SmPC before prescribing)

Indications: Symptomatic treatment of urge incontinence and/or increased urinary frequency and urgency as may occur in patients with overactive bladder syndrome. Available strengths: 2mg and 4mg x 28 prolonged-release capsules. Dosage and method of use: 4mg once daily except in patients with impaired liver or kidney function for whom recommended dose is 2mg once daily. In case of troublesome adverse reactions dose may be reduced from 4mg to 2mg once daily. ?Effect of treatment should be re-evaluated after 2-3 months. Take capsules with or without food and swallow whole. Not recommended for children. Contraindications: Hypersensitivity to the active substance or any excipient, urinary retention, uncontrolled narrow angle glaucoma, myasthenia gravis, severe ulcerative colitis, toxic megacolon. Special warnings and precautions for use: Use with caution in patients with significant bladder outlet obstruction at risk of urinary retention, gastrointestinal obstructive disorders, renal impairment, hepatic disease, autonomic neuropathy, hiatus hernia, at risk of decreased gastrointestinal motility, risk factors for QT prolongation including: congenital or documented acquired QT prolongation, electrolyte disturbances such as hypokalaemia, hypomagnesaemia and hypocalcaemia, bradycardia, relevant pre-existing cardiac diseases, concomitant administration of drugs known to prolong QT-interval including Class IA and Class III anti-arrhythmics. Avoid concomitant treatment with potent CYP3A4 inhibitors. Consider organic reasons for urge and frequency before treatment. Capsules contain lactose and sodium.

Patients with rare hereditary problems of galactose intolerance, the total lactase deficiency or glucose-galactose malabsorption should not take this medicine. Concomitant treatment with other drugs possessing antimuscarinic properties may result in more pronounced therapeutic effect and side effects. Conversely, therapeutic effect of tolterodine may be reduced by concomitant administration of muscarinic cholinergic receptor agonist. Effect of prokinetics like metoclopramide and cisapride may be decreased by tolterodine. As may cause accommodation disturbances and influence reaction time, ability to drive/ use machines may be negatively affected. Pregnancy/lactation: Not recommended during pregnancy; avoid during lactation. Side effects: For the full list of side effects consult SmPC. ‘Very Common’ ‘Common’ and ‘Serious’ side effects included. Very common (≥1/10): dry mouth; Common (≥1/100 to <1/10): sinusitis, dizziness, somnolence, headache, dry eyes, abnormal vision (including abnormal accommodation), dyspepsia, constipation, abdominal pain, flatulence, diarrhoea, dysuria, fatigue, peripheral oedema. Serious Uncommon (≥1/1000 to <1/100): hypersensitivity, cardiac failure, arrhythmia, urinary retention. Serious (unknown frequency): anaphylactoid reactions, tachycardia, angioedema. Cases of aggravation of symptoms of dementia have been reported after tolterodine therapy was initiated in patients taking cholinesterase inhibitors for treatment of dementia. MA number: PL 35533/0148-0149 Cost £12.89 for 4mg x 28, £11.60 for 2mg x 28. MAH: Aspire Pharma Ltd, Unit 4, Rotherbrook Court, Bedford Road, Petersfield, Hampshire GU32 3QG. Legal category: POM. Date last reviewed: January 2019. Version number: 1010083024 v 6.0

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Aspire Pharma Ltd on 01730 231148. 1010083335 v 2.0 February 2020

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